منابع مشابه
Repurposing of drug candidates for treatment of skin cancer
Skin cancers are highly prevalent malignancies that affect millions of people worldwide. These include melanomas and nonmelanoma skin cancers. Melanomas are among the most dangerous cancers, while nonmelanoma skin cancers generally exhibit a more benign clinical pattern; however, they may sometimes be aggressive and metastatic. Melanomas typically appear in body regions exposed to the sun, alt...
متن کاملChapter 771 Actinomadura R39 d-Ala d Ala Carboxypeptidase
bacterial penicillin-binding proteins and beta-lactamases. Antimicrob. Agents Chemother. 42(1), 1 17. [41] Davies, C., White, S.W., Nicholas, R.A. (2001). Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-Å resolution. J. Biol. Chem. 276(1), 616 623. [42] Nicola, G., Tomberg, J., Pratt, R.F., Nicholas, R.A., Davies, C. (2010). Crystal structures of coval...
متن کاملMutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY.
BACKGROUND Vancomycin-resistant enterococci are pathogenic bacteria that attenuate antibiotic sensitivity by producing peptidoglycan precursors that terminate in D-Ala-D-lactate rather than D-Ala-D-Ala. A key enzyme in effecting antibiotic resistance is the metallodipeptidase VanX, which reduces the cellular pool of the D-Ala-D-Ala dipeptide. RESULTS We constructed eleven mutants, using the r...
متن کاملThyroid ala perichondrial flaps for subglottic reconstruction.
OBJECTIVES/HYPOTHESIS Techniques available for reconstruction of the cricotracheal region in adults are currently suboptimal. We sought to 1) understand the anatomic basis for the thyroid ala perichondrial flap, 2) describe the technique of harvesting and intraluminal placement, and 3) learn the limitations of defects for which it can be used. STUDY DESIGN Cadaveric anatomical study. METHOD...
متن کامل[Council].
Council President: J. D. MacDonald President-Elect: J. H. Andrews Immediate Past President: G. C. Bergstrom Vice President: J. E. Leach Secretary: D. T. Beadle Treasurer: E. L. Stromberg Editor-in-Chief, Phytopathology: C. C. Mundt Editor-in-Chief, Plant Disease: K. L. Bowen Editor-in-Chief, Molecular Plant-Microbe Interactions: J. Stougaard Editor-in-Chief, Phytopathology News: M. L. Daughtrey...
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ژورنال
عنوان ژورنال: College & Research Libraries News
سال: 1986
ISSN: 2150-6698,0099-0086
DOI: 10.5860/crln.47.4.266